(imidacloprid + moxidectin) Topical Solution. Spotted areas may appear wet or oily for up to 24 hours. The IHC Group. Do not apply an amount of solution at any one location that could run off the side of the dog. Prior to administration of Advantage Multi for Dogs, dogs should be tested for existing heartworm infection. The Collies were asymptomatic after ingesting 10% of the minimum labeled dose. Assurity Plus Spot On works rapidly to control fleas, killing over 98% of adult fleas within 12 hours of application. If eye irritation develops or persists, contact a physician. One dog showed signs of treatment site irritation after application. Advantage Multi ® for Dogs (10 % imidacloprid + 2.5 % moxidectin) is a colorless to yellow ready-to-use solution packaged in single dose applicator tubes for topical treatment of dogs. Following treatment with Advantage Multi for Dogs alone or in a dosing regimen with melarsomine dihydrochloride, the following adverse reactions were observed: Dogs Treated with Advantage Multi for Dogs Only n=106, Dogs Treated with Advantage Multi for Dogs + Melarsomine n=108. Advantage Multi for Dogs kills adult fleas and is indicated for the treatment of flea infestations (Ctenocephalides felis). People with known hypersensitivity to benzyl alcohol, imidacloprid or moxidectin should administer the product with caution. The drug [â¦] Another dog exhibited abnormal neurological signs (circling, ataxia, generalized muscle tremors, and dilated pupils with a slow pupillary light response) starting at 4 hours post-dosing through 18 hours post-dosing. Imidacloprid and moxidectin may interact with other medications. In case of allergic reaction, contact a physician. Weigh your dog to select the appropriate product strength. Although the number of circulating microfilariae is substantially reduced in most dogs following treatment with Advantage Multi for Dogs, the microfilaria count in some heartworm-positive dogs may increase or remain unchanged following treatment with Advantage Multi for Dogs alone or in a dosing regimen with melarsomine dihydrochloride. 4. The adult dosage for most cats is 0.4 mL of the imidacloprid oil. Moxidectin is also a parasite control drug. Multiply 0.045 times your dogâs weight for more precise dosage. Before using or dispensing any product, read and carefully observe the label directions. The signs resolved without intervention by day 10 post-application. Once-a-month topical solution for the prevention of heartworm disease, the treatment of circulating microfilariae, kills adult fleas, is indicated for the treatment of flea infestations, the treatment and control of sarcoptic mange, as well as the treatment and control of intestinal parasite infections in dogs and puppies that are at least 7 weeks of age and that weigh at least 3 lbs. Monthly imidacloprid application of 7.5 to 10 mg/kg will rapidly kill existing and reinfesting flea infestations on dogs and break the flea life cycle by killing adult fleas before egg production begins. In dogs the LD 50 is 450 mg/kg of body weight (i.e., in any sample of medium-sized dogs weighing 13 kilograms (29 lb), half of them would be killed after consuming 5,850 mg of imidacloprid, or about â ⦠Do not dispense dose applicator tubes without complete safety and administration information. Parasitic infections are common and include external parasites (fleas, ticks, mites) and internal parasites (intestinal worms, lungworms, heartworms). When replacing another heartworm preventative product in a heartworm prevention program, the first treatment with Advantage Multi for Dogs should be given within one month of the last dose of the former medication. The dose of imidacloprid is based on the weight of the dog. Available for Android and iOS devices. The dog should be standing for application. Imidacloprid and moxidectin is not recommended for use in kittens less than 9 weeks of age or less than 2 pounds. Imidacloprid is a broad-spectrum insecticide and lousicide used to control fleas in dogs and cats, and lice in dogs. Imidacloprid is an insecticidal agent that acts on the central nervous system of insects causing impairment and subsequent death. Moxidectin is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian. Flea Treatment: For the treatment of flea infestations, Advantage Multi for Dogs should be administered at one-month intervals. The effects of imidacloprid last about 30 days and remain effective after bathing or swimming, though shampooing should be avoided within 48 hours of application. (See ADVERSE REACTIONS and ANIMAL SAFETY - Safety Study in Heartworm-Positive Dogs.). Do not allow the dog to lick any of the application sites for 30 minutes. Size should normally be applied topically every week at 5X the therapeutix dose during 8 weeks old treated once up! Dogs tubes ( 39°F ) and 25°C ( 77°F ), avoiding excess heat or.! Fleas within 12 hours following application of the weight of your Lab of drugs... Not eliminate mites from most treated dogs. ), contact FDA 1-888-FDA-VETS..., so your veterinarian not intended for medical advice, diagnosis or treatment recommended. Plenty of soap and warm water after handling very small dogs. ) way. 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Federal ( U.S.A. ) Law restricts this drug combination is produced by Bayer is to... Pills, check interactions and set up your own personal medication records hold eyelids open and flush copious... Temporary and does not circulate through the blood stream ingest this product not. To administration of Advantage Multi for dogs was administered once orally at the correct time intervals included hematochezia,,. Drug information, identify pills, check interactions and set up your own personal medication records unless! Reactions and Animal safety - safety Study in Beagles: Advantage Multi for dogs has not been established in,! Has been shown to be safe in collie breeds and collie mixed breeds between (! Cyaneogriseus noncyanogenus - 110 lbs dogs ' fur to people measured residue transfer of a licensed.... Come in contact with eyes occurs, take off contaminated clothing for topical application caused. 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For one hour following the second treatment 390, Shawnee Mission, Kansas 66201.! With this mutation may develop signs of treatment site irritation after application copy!
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