millions treated for hypothyroidism at risk for lung cancer

The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. Correlation is when two things seem to happen at the same time, in the same place, and/or in the same population. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. Also, what is oxidised stress??? I was sure that the paper had been discussed here shortly after publication in 2013, but cannot find the thread! [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. I think part of sharing information here on Inspire is the discussions about the articles we share. Compared to patients without hypothyroidism, those with a high TSH level before hospitalization stayed in the hospital 1.2 days longer and had a 49% higher risk of 30-day readmission and a 43% . I am just as much in the dark as some others on this site. I have so many women friends and family members who have recently been diagnosed with hypothyroidism and their doctors put them all on Synthyroid. Join the Patient & Caregiver Network. Allthewebsites Directory - A niche web directory offering website promotion and other webmaster resources. SayerJiis founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, SteeringCommittee Memberof the Global Non-GMO Foundation. [10] Hofer T, Desbaillets I, Hpfl G, Wenger RH, Gassmann M: Characterization of HIFD-1 alpha overexpressing Hela cells and implication for gene therapy. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. Thyroid dysfunction after immune checkpoint inhibitor treatment in a single-center Chinese cohort: a retrospective study The authors did not study whether individuals who took Synthroid actually developed lung cancer later in life. [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. Hypothyroidism can cause depression and, without treatment, the symptoms intensify and directly affect the mental state. But what can be done for patients who are at low The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the low thyroid, why call chemical poisoning hypothyroidism? When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. If the results show that TSH is high and T-4 is low, then the diagnosis . Very interesting article, thank you for sharing. Endocrinol. They found no significant correlation between T4 sales and breast, colorectal and gastriccancers, but did find a significant correlation for lung cancer (p < 0.05) corrected forsmoking and age. There are many links attached. Epub 2013 Mar 28. and our Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. The Flu Propaganda Matrix Continues To Promote Fea B Vitamins Slow Alzheimer's and Grey Matter Loss. Correlation is NOT causation. Just go on one of the thyroid sites and read the stories. Just another excuse for keeping us on doses that are too low. [10] Hofer T, Desbaillets I, Hpfl G, Wenger RH, Gassmann M: Characterization of HIFD-1 alpha overexpressing Hela cells and implication for gene therapy. The Goji Berry: The Jolly Super Food That Gives Yo How to Prevent and Treat Insect Bites Without Hars Supreme Court Rules Drug Companies Exempt From Law Spain Study Confirms Hemp Oil Cures Cancer without Wheatgrass Turns Gray Hair Back to Its Natural Color, Medicinal Cannabis Used To Prevent Cancer Growth. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). JavaScript is disabled. According to data from the National Health and Nutrition Examination Survey, years 1988-1994, [13] while 0.3% of the American population exhibits overt symptoms of hypothyroidism, 14 times more (4.3%) have so-called subclinical hypothyroidism only detected via blood work. PLoSone 2011, 11:e27547. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be. Patient characteristics. Non-small cell lung cancer is the most common type of lung cancer, accounting for about 81% of all cases. They only reappear when I need to fine tune the medication. bear in the big blue house characters; colne times obituaries this week Menu Toggle. To investigate the magnitude of the possible association between levothyroxine use and cancer risk, this retrospective c I hope that with increased knowledge we will all find the right road. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. My Endocrinologist was, and continues to be, open about the elevated risk for thyroid cancer due to the multiple. ', Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. Why not simply call it selenium deficiency? video where the doc is talking about the study , i wlll link study and video below. The first blood test typically done to diagnose hypothyroidism measures the level of thyroid-stimulating hormone (TSH) in the blood. Increased sensitivity to cold. ", Cure Alveolar Soft Part Sarcoma International, COMPLETED - Dana Farber Vaccine Clinical Trial (GVAX), Axitinib and Pembrolizumab (Keytruda) in Miami, US, TECENTRIQ (atezolizumab) by Genentech, Treatment of Non-Resectable Primary Tumor, Immune checkpoint inhibitors ICI (PD-1 and PD-L1 targeting drugs), Toxicity, problems and potentiation strategies, Treatment response criteria and evaluation/scanning problems/rare cases, treatment discontinuation/re-treatment, Side effects/complications of the local ablations, High intensity focused ultrasound (HIFU), Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, http://www.greenmedinfo.com/blog/study- ng-cancers. I wish I could say that my story was atypical. rocket fuel, pesticides, fluoride, which induce low thyroid function. The great open sky of imagination: for those who u Fermented Foods: Top 8 Reasons to Eat Them. I'm not saying that there Is no link between Synthroid and lung cancer. Salt, Sugar, Fat: 15 Shocking Facts From the Book Dear Doctor, Do You Really Know What Vaccines Cont Colloidal Gold: Discover the Benefits and Wonders, Scientists Explain Why HPV Vaccines Are Unsafe. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. Endocrinology 2008, 149:22412250. A study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new 'disease' case the patient is converted into a lifelong customer. I wonder if only t3 treatments are preferable than t4 and t3 ? I read somewhere about the work done many years ago which was mistakenly read and accepted 28 y/o F Low levels across the board for TSH, T3, and T4, Acid reflux drug linked to more than doubled risk of stomach cancer study, thyroiduk.org - further-reading - thyroid-diagnosis-and-treatment. I think there is always a lot of confusion with cause and cure. Ultimately, this Italian study brings further attention to one of a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. In my view the paper isn't worth the pixels used to display it on a screen. It does not seem to quantify the increased risk, and it keeps saying it is hyperthyroidism that causes the oxidised stress. Keep checking back for the register link to appear. [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. [3], An old clinical observation on the relationship between lung cancer and thyroid function reported that patients were characterized by a low concentration of T3 and an increased T4/T3 ratio due to a decrease of 5-monodeiodination (DI). Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the "low thyroid," why call chemical poisoning "hypothyroidism"? Respiratory system Hypothyroidism weakens the respiratory muscles and decreases lung function. Gestionar el consentimiento de las cookies. 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By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Cookie Notice Copyright 2008-2023 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM. Compression of the trachea, which may be positional, can occur with nodular goiters and thyroid cancer, and the latter can metastasize to the lungs. It's possible, for instance, that the reason both sales of Synthroid and the incidence of lung cancer increased is due to an environmental condition that affected both the thyroid and the lungs. Forgot account? But I for one, do appreciate anything that other members forward about potential links, causes, aids to healing, whatever you can them. Thank you for posting it, I agree we all need as much knowledge as we can get! millions treated for hypothyroidism at risk for lung cancer. Finally, they pointed out that T4, which is a synthetic form of thyroid hormone, might be avoided if T3 or the desiccated pig-derived form known as Armour Thyroid was used to control the oxidative-stress producing hydroperoxides. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to 'replacement' therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. 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Marketed as superior to traditional glandular forms extracted from pigs (whose endocrine glands are far more bioidentical than any other animal we know of) due to the dose-to-dose standardization of the so-called 'active ingredient' T4 versus the natural variations in hormone concentrations found in the 'real thing,' which incidentally contains a wide range of additional hormones including T1, T2, T3, all of which are vitally important. Could be another marmalade how would we know? J Exp Biol 2010, 213:28992911. (They noted that this age range corresponds to more than 80% of the consumers of the drug and to about 99% of all malignant cancers). Methods: The study group included 35 patients (15 women, 20 men, 65.8 7.1 years) with NSCLC in stage IIIB (n = 16, 45.7%) and IV (n = 19,54.3%) who were treated with nivolumab. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. It is very tormenting (for me anyhow) to not know why I got this disease. Maybe because they "treat" only with T4 and not T3? Endocrinology 1985, 117:12011208. But that's just me. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: [I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. Importance: Whether radioactive iodine (RAI) therapy for hyperthyroidism can increase cancer risk remains a controversial issue in medicine and public health. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. However, that information will still be included in details such as numbers of replies. florence nightingale concept 2 via de boleto In comparison, 62.4% of female and 37% of male . Factors found to be associated with mortality were age, senile dementia, congestive heart failure, chronic renal failure, and a history of cerebrovascular disease. PMID: 11929079, [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. 2004 Jun;9(2):157-79. The Dangers of Tylenol: Is it Time to for the FDA Chile: Psychiatrist Leads Crusade To Legalize Mari 13 Things Sure To Slow Down Your Metabolism. For a better experience, please enable JavaScript in your browser before proceeding. It may not display this or other websites correctly. Results indicate that treatment with levothyroxine was linked with significantly increased mortality (hazard ratio = 1.19). Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Symptoms. Unfortunately, it's quite typical. Even in the mildest form, hypothyroidism affects the heart. I invite those interested to read it and perhaps we can have a discussion on this study. PLoSone 2011, 11:e27547. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)". A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Link posted. Increased sleepiness. Just for entertainment value take a look at some more dodgy correlations : I rather liked the correlation between consumption of orange marmalade and birth rate - in the years after the second world war if I remember correctly. I have no further scientific evidence. Cancer-related fatigue (CRF) is common in lung cancer survivors and can occur at any point in the care continuum. 500+ pages of Natural Medicine Alternatives and Information. A study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related diseases.. I very much appreciate the information you shared. I have always found this condition a riddle. May be of interest: Study: Millions Treated for Hypothyroidism At Risk for, Non-small cell lung cancer - Adenocarcinoma, Non-small cell lung cancer - Squamous cell, Top 5 Questions to Ask Your Lung Cancer Doctor, Patient & Caregiver Network Member Resources, Not A Member Yet? It is worth reading. What I am personally saying issince I personally have a disease that may kill me, I sure as heck have every right to find out ALL I can about it. If you are already a member, please, Levothyroxine and lung cancer in females: the importance of oxidative stress, recent announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs. In an attempt to show causation, the article notes "patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e.

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